Raloxifene is more than 95 bound to plasma proteins see Clinical Pharmacology (.3 ). Women with active or past history of venous thromboembolism should not take Evista see Contraindications (.1 ). Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Table 7 presents efficacy and selected safety outcomes. Evista - Clinical Pharmacology Mechanism of Action Raloxifene is an estrogen agonist/antagonist, commonly referred to as a selective estrogen receptor modulator (serm). In addition, women taking Evista should be advised to move about periodically during prolonged travel. Raloxifene and the monoglucuronide conjugates are highly (95) bound to plasma proteins. Take Evista exactly as prescribed by your doctor. Being still for a long time (such as sitting still during a long car or airplane trip or being in bed after surgery) can increase your risk of blood clots. History of Hypertriglyceridemia when Treated with Estrogens Limited clinical data suggest that some women with a history of marked hypertriglyceridemia (.6 mmol/L or 500 mg/dL) in response to treatment with oral estrogen or estrogen plus progestin may develop increased levels of triglycerides when treated with Evista. Stop taking Evista and call your doctor if you have: leg pain or a feeling of warmth in the lower leg (calf).
Evista is used to treat and prevent osteoporosis in postmenopausal women.
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Evista official prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions, pharmacology and more. Coupon, value and Save: Save as high as 80 on prescription medications How Does It Work: This program is for people NO insurance, NO drug coverage, self employed, donut hole seniors.
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No other metabolites have been detected, providing strong evidence that raloxifene is not metabolized by cytochrome P450 ez ticket promo code pathways. If you would like more information about Evista, talk with your doctor. Do not take extra medicine to make up the missed dose. 5.4 Premenopausal Use There is no indication for premenopausal use of Evista. In a subset of postmenopausal women followed for up to 8 years from randomization in more to the end of core, Evista, 60 mg administered once daily, reduced the incidence of invasive breast cancer by 60 in women assigned Evista (N1355) compared with placebo (N1286). Osteoporosis Recommendations, Including Calcium and Vitamin D Supplementation For osteoporosis treatment or prevention, patients should be instructed to take supplemental calcium and/or vitamin D if intake is inadequate. Raloxifene appears to act as an estrogen agonist in bone.
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